Impulsivity and Parkinson's disease: More than just disinhibition
Identifieur interne : 001940 ( Main/Exploration ); précédent : 001939; suivant : 001941Impulsivity and Parkinson's disease: More than just disinhibition
Auteurs : Francesca Antonelli [Canada] ; Nicola Ray [Canada] ; Antonio P. Strafella [Canada]Source :
- Journal of the neurological sciences [ 0022-510X ] ; 2011.
Descripteurs français
- Pascal (Inist)
English descriptors
- KwdEn :
- Deep Brain Stimulation (methods), Dopamine, Dopamine Agonists (therapeutic use), Encephalon, Humans, Impulse control disorder, Impulsive Behavior (etiology), Impulsive Behavior (therapy), Nervous system diseases, Parkinson Disease (complications), Parkinson disease, Subthalamic Nucleus (physiology), Subthalamic nucleus.
- MESH :
- chemical , therapeutic use : Dopamine Agonists.
- complications : Parkinson Disease.
- etiology : Impulsive Behavior.
- methods : Deep Brain Stimulation.
- physiology : Subthalamic Nucleus.
- therapy : Impulsive Behavior.
- Humans.
Abstract
In the last few years it has become clear that impulsivity is a complex behaviour composed of different domains and dependent on different neural networks. The proposed pathogenetic mechanisms for the emergence of impulsivity disorders in Parkinson's Disease (PD) can be broadly separated into three potentially interacting processes: the contribution of premorbid susceptibility to impulsivity, the contribution of the disease itself to the behaviour and the potential contribution of therapeutic agents. Growing evidence suggests that dopamine and the subthalamic nucleus are playing a certain role in the pathophysiology of different aspects of impulsivity. In this review, we summarise the main concepts defining various components of impulsivity both in healthy subjects and patients affected by PD.
Url:
Affiliations:
Links toward previous steps (curation, corpus...)
- to stream PascalFrancis, to step Corpus: 000266
- to stream PascalFrancis, to step Curation: 000997
- to stream PascalFrancis, to step Checkpoint: 000259
- to stream Main, to step Merge: 001A34
- to stream Pmc, to step Corpus: 000720
- to stream Pmc, to step Curation: 000720
- to stream Pmc, to step Checkpoint: 000937
- to stream PubMed, to step Corpus: 000B54
- to stream PubMed, to step Curation: 000B54
- to stream PubMed, to step Checkpoint: 000B54
- to stream Ncbi, to step Merge: 000E99
- to stream Ncbi, to step Curation: 000E99
- to stream Ncbi, to step Checkpoint: 000E99
- to stream Main, to step Merge: 001716
- to stream Main, to step Curation: 001940
Le document en format XML
<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en" level="a">Impulsivity and Parkinson's disease: More than just disinhibition</title><author><name sortKey="Antonelli, Francesca" sort="Antonelli, Francesca" uniqKey="Antonelli F" first="Francesca" last="Antonelli">Francesca Antonelli</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Toronto Western Research Institute and Hospital, UHN, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>PET Imaging Centre, Centre for Addiction and Mental Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Ray, Nicola" sort="Ray, Nicola" uniqKey="Ray N" first="Nicola" last="Ray">Nicola Ray</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Toronto Western Research Institute and Hospital, UHN, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>PET Imaging Centre, Centre for Addiction and Mental Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Strafella, Antonio P" sort="Strafella, Antonio P" uniqKey="Strafella A" first="Antonio P." last="Strafella">Antonio P. Strafella</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Toronto Western Research Institute and Hospital, UHN, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>PET Imaging Centre, Centre for Addiction and Mental Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author></titleStmt><publicationStmt><idno type="wicri:source">INIST</idno><idno type="inist">11-0499922</idno><date when="2011">2011</date><idno type="stanalyst">PASCAL 11-0499922 INIST</idno><idno type="RBID">Pascal:11-0499922</idno><idno type="wicri:Area/PascalFrancis/Corpus">000266</idno><idno type="wicri:Area/PascalFrancis/Curation">000997</idno><idno type="wicri:Area/PascalFrancis/Checkpoint">000259</idno><idno type="wicri:explorRef" wicri:stream="PascalFrancis" wicri:step="Checkpoint">000259</idno><idno type="wicri:doubleKey">0022-510X:2011:Antonelli F:impulsivity:and:parkinson</idno><idno type="wicri:Area/Main/Merge">001A34</idno><idno type="wicri:source">PMC</idno><idno type="url">http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3440306</idno><idno type="RBID">PMC:3440306</idno><idno type="wicri:Area/Pmc/Corpus">000720</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Corpus" wicri:corpus="PMC">000720</idno><idno type="wicri:Area/Pmc/Curation">000720</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Curation">000720</idno><idno type="wicri:Area/Pmc/Checkpoint">000937</idno><idno type="wicri:explorRef" wicri:stream="Pmc" wicri:step="Checkpoint">000937</idno><idno type="wicri:source">PubMed</idno><idno type="wicri:Area/PubMed/Corpus">000B54</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Corpus" wicri:corpus="PubMed">000B54</idno><idno type="wicri:Area/PubMed/Curation">000B54</idno><idno type="wicri:explorRef" wicri:stream="PubMed" wicri:step="Curation">000B54</idno><idno type="wicri:Area/PubMed/Checkpoint">000B54</idno><idno type="wicri:explorRef" wicri:stream="Checkpoint" wicri:step="PubMed">000B54</idno><idno type="wicri:Area/Ncbi/Merge">000E99</idno><idno type="wicri:Area/Ncbi/Curation">000E99</idno><idno type="wicri:Area/Ncbi/Checkpoint">000E99</idno><idno type="wicri:doubleKey">0022-510X:2011:Antonelli F:impulsivity:and:parkinson</idno><idno type="wicri:Area/Main/Merge">001716</idno><idno type="wicri:Area/Main/Curation">001940</idno><idno type="wicri:Area/Main/Exploration">001940</idno></publicationStmt><sourceDesc><biblStruct><analytic><title xml:lang="en" level="a">Impulsivity and Parkinson's disease: More than just disinhibition</title><author><name sortKey="Antonelli, Francesca" sort="Antonelli, Francesca" uniqKey="Antonelli F" first="Francesca" last="Antonelli">Francesca Antonelli</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Toronto Western Research Institute and Hospital, UHN, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>PET Imaging Centre, Centre for Addiction and Mental Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Ray, Nicola" sort="Ray, Nicola" uniqKey="Ray N" first="Nicola" last="Ray">Nicola Ray</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Toronto Western Research Institute and Hospital, UHN, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>PET Imaging Centre, Centre for Addiction and Mental Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author><author><name sortKey="Strafella, Antonio P" sort="Strafella, Antonio P" uniqKey="Strafella A" first="Antonio P." last="Strafella">Antonio P. Strafella</name><affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Toronto Western Research Institute and Hospital, UHN, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation><affiliation wicri:level="4"><inist:fA14 i1="02"><s1>PET Imaging Centre, Centre for Addiction and Mental Health, University of Toronto</s1><s2>Toronto</s2><s3>CAN</s3><sZ>1 aut.</sZ><sZ>2 aut.</sZ><sZ>3 aut.</sZ></inist:fA14><country>Canada</country><placeName><settlement type="city">Toronto</settlement><region type="state">Ontario</region></placeName><orgName type="university">Université de Toronto</orgName></affiliation></author></analytic><series><title level="j" type="main">Journal of the neurological sciences</title><title level="j" type="abbreviated">J. neurol. sci.</title><idno type="ISSN">0022-510X</idno><imprint><date when="2011">2011</date></imprint></series></biblStruct></sourceDesc><seriesStmt><title level="j" type="main">Journal of the neurological sciences</title><title level="j" type="abbreviated">J. neurol. sci.</title><idno type="ISSN">0022-510X</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Deep Brain Stimulation (methods)</term><term>Dopamine</term><term>Dopamine Agonists (therapeutic use)</term><term>Encephalon</term><term>Humans</term><term>Impulse control disorder</term><term>Impulsive Behavior (etiology)</term><term>Impulsive Behavior (therapy)</term><term>Nervous system diseases</term><term>Parkinson Disease (complications)</term><term>Parkinson disease</term><term>Subthalamic Nucleus (physiology)</term><term>Subthalamic nucleus</term></keywords><keywords scheme="MESH" type="chemical" qualifier="therapeutic use" xml:lang="en"><term>Dopamine Agonists</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Parkinson Disease</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Impulsive Behavior</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Deep Brain Stimulation</term></keywords><keywords scheme="MESH" qualifier="physiology" xml:lang="en"><term>Subthalamic Nucleus</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Impulsive Behavior</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Humans</term></keywords><keywords scheme="Pascal" xml:lang="fr"><term>Maladie de Parkinson</term><term>Trouble du contrôle des impulsions</term><term>Pathologie du système nerveux</term><term>Encéphale</term><term>Dopamine</term><term>Noyau sousthalamique</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">In the last few years it has become clear that impulsivity is a complex behaviour composed of different domains and dependent on different neural networks. The proposed pathogenetic mechanisms for the emergence of impulsivity disorders in Parkinson's Disease (PD) can be broadly separated into three potentially interacting processes: the contribution of premorbid susceptibility to impulsivity, the contribution of the disease itself to the behaviour and the potential contribution of therapeutic agents. Growing evidence suggests that dopamine and the subthalamic nucleus are playing a certain role in the pathophysiology of different aspects of impulsivity. In this review, we summarise the main concepts defining various components of impulsivity both in healthy subjects and patients affected by PD.</div></front></TEI><affiliations><list><country><li>Canada</li></country><region><li>Ontario</li></region><settlement><li>Toronto</li></settlement><orgName><li>Université de Toronto</li></orgName></list><tree><country name="Canada"><region name="Ontario"><name sortKey="Antonelli, Francesca" sort="Antonelli, Francesca" uniqKey="Antonelli F" first="Francesca" last="Antonelli">Francesca Antonelli</name></region><name sortKey="Antonelli, Francesca" sort="Antonelli, Francesca" uniqKey="Antonelli F" first="Francesca" last="Antonelli">Francesca Antonelli</name><name sortKey="Ray, Nicola" sort="Ray, Nicola" uniqKey="Ray N" first="Nicola" last="Ray">Nicola Ray</name><name sortKey="Ray, Nicola" sort="Ray, Nicola" uniqKey="Ray N" first="Nicola" last="Ray">Nicola Ray</name><name sortKey="Strafella, Antonio P" sort="Strafella, Antonio P" uniqKey="Strafella A" first="Antonio P." last="Strafella">Antonio P. Strafella</name><name sortKey="Strafella, Antonio P" sort="Strafella, Antonio P" uniqKey="Strafella A" first="Antonio P." last="Strafella">Antonio P. Strafella</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
EXPLOR_STEP=$WICRI_ROOT/Wicri/Canada/explor/ParkinsonCanadaV1/Data/Main/Exploration
HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001940 | SxmlIndent | more
Ou
HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001940 | SxmlIndent | more
Pour mettre un lien sur cette page dans le réseau Wicri
{{Explor lien
|wiki= Wicri/Canada
|area= ParkinsonCanadaV1
|flux= Main
|étape= Exploration
|type= RBID
|clé= Pascal:11-0499922
|texte= Impulsivity and Parkinson's disease: More than just disinhibition
}}
| This area was generated with Dilib version V0.6.29. |  |